Professor at the University of Paderborn, Prof. Dr. Jan Paradies recently discovered an unprecedented reaction in which an entire molecular fragment migrates to another location within the particle. "It's every scientist's dream to find something new enough to be included as basic information in textbooks," he says. He also made the following statements about the invention they made.
“Such reorganizations are extremely rare, but invaluable as they only move in a very specific way and only yield a single product. In the future, for example, this will enable the simple and efficient production of bioactive substances such as health. He stated that his inventions will have positive results in terms of beneficial ingredients in food products. The results are published in the journal Angewandte Chemie.
Chemistry deals with the transformation of matter, specifically the conversion of one molecule to another. “The foundations of the reactions featured here were already established in the 18th and 19th centuries, so you won't find anything new about it every day,” Paradies says.
Types of Chemical Reactions in Brief
- Combination reaction:
Two or more compounds combine to form a compound. A + B → AB
- Decomposition reaction:
The opposite of a combination reaction – a complex molecule is broken down to make simpler ones. AB → A + B
- Precipitation reaction:
Two solutions of soluble salts are mixed to form an insoluble solid (precipitate). A + Soluble salt B → Precipitate + soluble salt C
- Neutralization reaction:
An acid and a base react with each other. Usually the product of this reaction is salt and water. Acid + Base → Salt + Water
- Combustion reaction:
Oxygen combines with a compound to form carbon dioxide and water. These reactions are exothermic, meaning they give off heat. CH4 + 2O2 → 2H2O + CO2
- Displacement reaction:
An element is combined with another element in a compound. A + BC → AC + B
However, this is exactly what Paradies and his team at the Center for Sustainable Systems Design (CSSD) at the University of Paderborn have now managed to achieve. Specifically, this involves the complete sliding of a large, nitrogen-attached organic moiety to one distal side in the molecular scaffold. It moves five carbon atoms further and forms a new carbon-carbon bond there. Rearrangement reactions like this are one of the most useful tools for the construction of organic scaffolds.
Paradies announced that they had “discovered a new rearrangement of transient ammonium enolates.”
These are intermediates used, for example, in the functionalization of carboxylic acid derivatives. Unlike other electrophilic rearrangements, enolates are produced via an intramolecular reaction. Electrophilic rearrangements are chemical. reactions in which atoms in the same molecule are rearranged.
This eventually creates a new chemical compound.
The momentum behind the reaction is the formation of an energetically more useful product as opposed to the starting material.
Visualize it this way: it's comfortable on the couch, it's much more comfortable getting into bed. It's not just what we want, it's something nature wants as well.”
Günceleme: 04/07/2022 19:23